DTEAssurance: Assurance Methods for Clinical Trials with a Delayed Treatment Effect

Provides functions for planning clinical trials subject to a delayed treatment effect using assurance-based methods. Includes two 'shiny' applications for interactive exploration, simulation, and visualisation of trial designs and outcomes. The methodology is described in: Salsbury JA, Oakley JE, Julious SA, Hampson LV (2024) "Assurance methods for designing a clinical trial with a delayed treatment effect" <doi:10.1002/sim.10136>, Salsbury JA, Oakley JE, Julious SA, Hampson LV (2024) "Adaptive clinical trial design with delayed treatment effects using elicited prior distributions" <doi:10.48550/arXiv.2509.07602>.

Version: 1.0.0
Depends: R (≥ 4.0)
Imports: SHELF, shiny, stats, survival, nleqslv, nph, nphRCT, dplyr, rjags, rpact, magrittr, rlang, future.apply
Suggests: testthat (≥ 3.0.0)
Published: 2025-10-14
DOI: 10.32614/CRAN.package.DTEAssurance (may not be active yet)
Author: James Salsbury ORCID iD [aut, cre]
Maintainer: James Salsbury <jsalsbury1 at sheffield.ac.uk>
License: MIT + file LICENSE
URL: https://jamesalsbury.github.io/DTEAssurance/
NeedsCompilation: no
Materials: README, NEWS
CRAN checks: DTEAssurance results

Documentation:

Reference manual: DTEAssurance.html , DTEAssurance.pdf

Downloads:

Package source: DTEAssurance_1.0.0.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): DTEAssurance_1.0.0.tgz, r-oldrel (x86_64): DTEAssurance_1.0.0.tgz

Linking:

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