Provides statistical tools to analyze heterogeneous effects of rare variants within genes that are associated with multiple traits. The package implements methods for assessing pleiotropic effects and identifying allelic heterogeneity, which can be useful in large-scale genetic studies. Methods include likelihood-based statistical tests to assess these effects. For more details, see Lu et al. (2024) <doi:10.1101/2024.10.01.614806>.
| Version: | 0.1.9 |
| Imports: | dplyr, magrittr, readr, mvtnorm, stats |
| Suggests: | knitr, rmarkdown, testthat (≥ 3.0.0) |
| Published: | 2024-10-16 |
| DOI: | 10.32614/CRAN.package.ALLSPICER |
| Author: | Wenhan Lu [aut, cre] |
| Maintainer: | Wenhan Lu <wlu at broadinstitute.org> |
| License: | MIT + file LICENSE |
| NeedsCompilation: | no |
| Materials: | README |
| CRAN checks: | ALLSPICER results |
| Reference manual: | ALLSPICER.pdf |
| Package source: | ALLSPICER_0.1.9.tar.gz |
| Windows binaries: | r-devel: ALLSPICER_0.1.9.zip, r-release: ALLSPICER_0.1.9.zip, r-oldrel: ALLSPICER_0.1.9.zip |
| macOS binaries: | r-devel (arm64): ALLSPICER_0.1.9.tgz, r-release (arm64): ALLSPICER_0.1.9.tgz, r-oldrel (arm64): ALLSPICER_0.1.9.tgz, r-devel (x86_64): ALLSPICER_0.1.9.tgz, r-release (x86_64): ALLSPICER_0.1.9.tgz, r-oldrel (x86_64): ALLSPICER_0.1.9.tgz |
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