Placental Epigenetic Clock to Estimate Aging by DNA Methylation

---

Documentation for package ‘rplec’ version 0.1.3

• DESCRIPTION file.
• User guides, package vignettes and other documentation.

Help Pages

aging	Residual DNA-methylation-based (DNAm) gestational age
beta_v_indices	Indices for random beta values
bmiq_norm_450k	Normalize DNA methylation values
download_beta_values_case	Access Beta values at individual CpG sites for case group
download_beta_values_control	Access Beta values at individual CpG sites for control group
ga	Gestational age for both case and control groups
ipla	Identify placental aging
phenotype	Phenotype for both case and control groups
plec	Estimate DNA-methylation-based gestational age
plec_int_coef	Intercept and coefficients of placental epigenetic clock
plec_scaler_mean	Mean values of the scalers of placental epigenetic clock
plec_scaler_scale	Scale values of the scalers of placental epigenetic clock
probe_info_450k	Probe info for 450K
qc	Perform quality control